I usually keep on the move, making a few safe havens in the area I am in, spending my days looting and stocking the safe houses with supplies. Going in a spiralish pattern. I usually only barricade a couple of places, the rest sheets. My favorite safe houses are the medical clinic, the gas station (the pumps have cover, nice to be outside in the rain with views.) and the bar, it's so nice to have the bar impede zombies.