So as far as my experience goes, when a random wound gets infected, it's not a big deal. Just a takes a bit longer to heal I guess?
Would be cool if infections would actually make you sick sometimes.
Also, amputating limbs would also be dope. Not sure why this just popped into my head, but imagine playing on a server where someone has a high medical skill, you get bit in the hand for example, and hey might as well take the chance and get that hand amputated. You're gonna die anyways, so an amputated hand is worth the risk!