Yeah but your character performs actions slower when freezing or depressed. The freezing or depression themselves might not kill you right away, but that zombie chasing you might, now that you can't run away fast enough! Or your timing is off because of the slower melee swings when it comes to that.
I agree with Mr_Sunshine that you want to minimize all 'disadvantageous conditions' whenever possible.
It's like ignoring dash lights in your car. Can you get away with ignoring them? Probably. Should you ignore them? Probably not. If you do, you are now in a compromised situation driving your car. The likelihood of a successful drive just decreased. Is it worth the risk?