I have removed mods from the save, loaded into it and tested the layouts, it looks like I can plumb the sinks in any of the layouts you mentioned.
This would likely mean that one of your mods is likely causing the issue, since I cannot replicate it on this same save without mods, unless I misunderstood the issue?
Your graphic drivers look out of date, which may prevent the game from properly launching.
I suggest updating them from your CPU website:
https://www.intel.com/content/www/us/en/products/sku/75104/intel-core-i34000m-processor-3m-cache-2-40-ghz/downloads.html