It is completely random and I can sometimes start playing and everything will work perfectly fine, but upon closing and opening the game again, it may stop working and the only solution is to reset your PC. (Tried opening and closing the game again multiple times but it doesn't work.)
Has been a common occurrence at least since 41.71 when I first started playing the game and persists on 41.2, 41.73 and 41.76.
OS: Linux Mint 20.3 64-bit
Display Server: X11
CPU: Intel i5-3330 (4) @ 3.200GHz
GPU: NVIDIA GeForce GTX 750 Ti