Irl claustrophobia and Agoraphobia are very manageable with Beta blockers such as atenolol and propanolol. Taking beta blockers after being panicked from claustrophobia or agoraphobia doesn't lower your panicked state. Perhaps a buff of beta blockers or a change in the mechanics of How panic is induced by those traits. Or an addition of benzodiazepines as an acute panic reducer, and a de buff to beta blockers to a milder panic reliever. Benzodiazepines do have sedative effects though.